Almost all the common hardware is designed for 3/8. I shared your idea of using 1/2" line back when I was at this fuel system stage, but found planning a 1/2" system forward of the fuel value both difficult and fruitless.
The common parts were designed from the ground up to work well together, and the common configurations were designed to manage the risks of powered flight. Of course the homebuilder
can do whatever they want, but it doesn't mean that they should

Tens of thousands of planes flying with a system which works reliably and is easy to maintain are a safe bet to copy.
Each common device (gascolater, transducer, filter, selector valve, standby pump, etc) offers a restriction to flow anyway, so the larger lines don't help much overall unless you up-size those parts too. You can source larger devices, but then you run into the "Law of Unintended Consequences".... like things not fitting in the spaces provided, or things being incompatible with avionics, plus the unforeseeable etc. etc. etc.
By the by, when designing a system from scratch the designer needs to think about flow rate and pressure independently, they are not proportional to each-other. So both flow and pressure are independent considerations for a fuel injected engine, as noted by Schu. Bendix for Lycoming needs 15psi for normal Ops, 12psi to idle, not more than 45psi at any time. Improvements which improve pressure don't necessarily improve flow rate.